What is clinical library?

The clinical dataset constructed for multi-institutional research purposes by collecting basic clinical data (Baseline DB) and
disease-specific clinical data in standardized formats from electronic medical records and clinical databases established at
participating institutions.※ Cancer (2022-2025), respiratory, and cardiovascular diseases

In-house clinical library system architecture

1. Baseline DB

(Definition) Clinical database established in the form of CDW according to common standards of participating institutions
regardless of diseases
(Model) It is composed of 6 groups and 39 tables and refers to OMOP-CDM model as data model.

2. Cancer clinical library

(Definition) Cancer clinical database established by standardizing* 10 cancer clinical data stored in participating medical
institutions’ electronic medical records (EMR) and clinical data warehouse (CDW) by cancer type
*Based on item definition through verification by cancer clinical associations.
(Model) Each cancer type schema is composed of five groups: patient, diagnosis, tests, treatment, and follow-up observation.
Intermediate classifications are designed based on the characteristics of each cancer type.

Stage of establishing clinical library

Establishment of clinical library (datasets generated by hospitals and medical institutions)
with the participation of 15 major hospitals in Korea

[ Cancer library data model ]

Cancer clinical library data collection plan

Cancer clinical library (datasets generated by hospitals and medical institutions) data standardization process

2. Identifying cancer-specific items based on discussion with major domestic associations and professionals

3. Determining standard items and designing database based on discussion among medical professionals
from K-CURE participating hospitals

Cancer clinical library standard and quality management through the operation of standardization quality control subcommittee

・Data Provision Deliberation Committee and Data Export Review Committee including independent professionals review the adequacy of utilization
and anonymization and IRB conducts review. After that, the data is provided by Safety Utilization Center